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Opioids may be recommended as a second-line pharmacotherapy but have risks including overdose and death. Cannabis has been shown to be effective for treating nerve pain without the risk of fatal poisoning.
Over the last few years, Cannabidiol (CBD) has exploded into the world of health and wellness.
The endocannabinoid system is involved in a host of homeostatic and physiologic functions, including modulation of pain and inflammation.
Access the list here: https://www.tga.gov.au/pain-randomised-controlled-trials-and-other-studies
by Mary Barna Bridgeman, PharmD, BCPS, BCGP and Daniel T. Abazia, PharmD, BCPS, CPE The purpose of this article is to review the historical significance of the use of medicinal cannabis and to discuss its pharmacology, pharmacokinetics, and select evidence on medicinal uses, as well as to describe the implications of evolving medicinal cannabis regulations and...
by Gregory T Carter, Simone P Javaher, Michael HV Nguyen, Sharon Garret & Beatriz H Carlini The field of pain medicine is at a crossroads given the epidemic of addiction and overdose deaths from prescription opioids. Cannabis and its active ingredients, cannabinoids, are a much safer therapeutic option. Despite being slowed by legal restrictions and...
by Orrin Devinsky, Maria Roberta Cilio, Helen Cross, Javier Fernandez‐Ruiz, Jacqueline French, Charlotte Hill, Russell Katz, Russell Katz, Vincenzo Di Marzo, Didier Jutras‐Aswad, William George Notcutt, Jose Martinez‐Orgado, Philip J. Robson, Brian G. Rohrback, Elizabeth Thiele, Benjamin Whalley, Daniel Friedman.  The antiepileptic mechanisms of CBD are not known, but may include effects on the equilibrative...
by Wen-Juan Huang, Wei-Wei Chen and Xia Zhang Depression and pain co-exist in the majority of patients and often contribute to high mortality. Most patients who suffer from the comorbid depression and pain are not responsive to pharmacological treatments that address either the pain or depression, exacerbating this comorbidity disorder. Cannabinoids present in marijuana are...
There is rising popularity of cannabis and CBD to treat a variety of health issues, however there is still much fear around its impact and potential dependencies. Here is the report from the World Health Organisation on drug dependence.
A patient may only register for a medical marijuana certificate if he or she is a Connecticut resident being treated for a debilitating medical condition by a Connecticut-licensed physician or advanced practice registered nurse.
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